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Carsten
Burkhardt's Web
Project Paeonia
- The
Peony Library
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Paeonia-Literatur
2001
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Chen,
Y.C., Mu, H.c., Liu, S.q: Determination of Paeoniflorin in
Paeonia Lactiflora Pall and Traditional Chinese Pharmaceutical
Preparations by HPCE, Vol.16 Iss.6 P.448-449 (2001) WEST CHINA
JOURNAL OF PHARMACEUTICAL SCIENCES (direct
link to Infotrieve)
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Ferguson,
Diane, Sang, Tao:
BIOLOGICAL SCIENCES - EVOLUTION - Speciation
through homoploid hybridization between allotetraploids in
peonies (Paeonia)
Proc Natl Acad Sci U S A. 2001 March 27; 98(7): 39153919.
doi: 10.1073/pnas.061288698. Published
online
2001 March 20.[Phylogenies
of Adh1 and Adh2 genes suggest that a widespread Mediterranean
peony, Paeonia officinalis, is a homoploid hybrid species between
two allotetraploid species, Paeonia peregrina and a member of the
Paeonia arietina species group. Three phylogenetically distinct
types of Adh sequences have been identified from both accessions
of P. officinalis, of which two types are most closely related to
the two homoeologous Adh loci of the P. arietina group and the
remaining type came from one of the two Adh homoeologs of P.
peregrina. The other Adh homoeolog of P. peregrina was apparently
lost from the hybrid genome, possibly through backcrossing with
the P. arietina group. This is a documentation of homoploid
hybrid speciation between allotetraploid species in nature. This
study suggests that hybrid speciation between allotetraploids can
occur without an intermediate stage of genome diploidization or a
further doubling of genome size. ]
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Fulton,
T A: Chilling requirements of Paeonia
cultivars. Sci hortic Vol.89 Iss.3 P.237 (2001)
[Summary: Dormant second year potted
plants of Paeonia 'Coral Sunset', 'Monsieur Jules Elie', and
'Sarah Bernhardt' were placed into three chilling regimes
(constant 1, 4, or 7degreeC) for different durations (3, 6, 9, or
12 weeks) to ascertain their chilling requirements for shoot and
flower production. Chilling was followed by forcing for up to 5
weeks at 18degreeC, then plants were maintained in a controlled
greenhouse until flowering had finished. Mean number of shoots
and flowers per plant were recorded and the time taken for shoots
to sprout was calculated. Control plants (forced immediately
without chilling) produced no shoots or flowers. For all
cultivars, the proportion of plants that sprouted, and the mean
number of shoots and flowers increased as plants were subjected
to colder chilling temperatures, or longer chilling durations.
However, there were no significant within-cultivar differences
between different treatments of 9 weeks or more. The time taken
for sprouting to occur after the completion of each chilling
treatment consistently decreased as the duration of the chilling
treatment increased. In most cases, lower chilling temperatures
lead to more rapid sprouting once plants were placed in the
18degreeC forcing conditions. When a simple model was fitted
where the chilling temperature and duration of each treatment was
described by a cumulative normal curve rising from zero to some
maximum value (or potential) once adequate chilling had been
received, we found that temperatures of 4 and 7degreeC provided
only 83 and 59%, respectively, of the chilling accumulated per
unit time at 1degreeC. 'Coral Sunset', an interspecific hybrid
early flowering type, required the greatest amount of chilling to
sprout consistently, while 'Sarah Bernhardt', a very late
flowering type, required the least. Of the three cultivars,
'Sarah Bernhardt' also required the least amount of chilling to
achieve its potential shoot and flower numbers, while 'Monsieur
Jules Elie', a mid-season flowering type, required the most
chilling to achieve the same end for these two variables. This
suggests that the response to spring temperatures as well as
chilling influences the time of flowering.]
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Gast, K.,
McLaren, J., Kampjes, R:
Identification of Bud Maturity Indicators for Fresh Cut
Peony Flowers ACTA
HORTICULTURAE Iss.543 P.317-326 (2001)
(direct
link to Infotrieve)
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IvanovaA
:GC-MS Analysis and Anti-Microbial Activity of Acidic
Fractions Obtained from Paeonia peregrina and Paeonia tenuifolia
Roots ZEITSCHRIFT FUR
NATURFORSCHUNG C 57(7-8):624-628 2002 (direct
link to Infotrieve)
[Summary: Fourteen aromatic and 24 aliphatic acids were
determined by GC-MS analysis of acidic fractions obtained from
Paeonia peregrina and Paeonia tenuifolia roots. Benzoic acid and
its monohydroxy-, dihydroxy- and trihydroxy-derivatives are the
main acid components of both Paeonia species. Some fractions
could serve as a source of benzoic, 4-hydroxybenzoic, vanillic
and gallic acids, as well as of ethyl gallate. The fractions
inhibited the growth of Staphylococcus aureus, Escherichia coli
and Candida albicans.]
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Joo, J.
H., Lee, N. H., Ryu, G., Choi, B. W., Lee, B. H., Jung, D. S.,
Park, E. K: A New Antioxidant Monoterpene Glycoside,
alpha-Benzoyloxypaeoniflorin from Paeonia suffruticosa .ARCHIVES
OF PHARMACEUTICAL RESEARCH Vol.24 Iss.2 P.105-108 (2001)
(direct
link to Infotrieve)
[Summary: Alpha-benzoyloxypaeoniflorin (1), a new
antioxidant monoterpene alpha-glycoside anomer was isolated from
Paeonia suffruticosa along with known compounds,
beta-benzoyloxypaeoniflorin (2), paeonolide, paeoniflorin and
mudanpioside H. The structure of 1 has been determined by
comparing spectral data with those of beta-benzoyloxypaeoniflorin
(2). Compound 1 exhibited moderately potent radical scavenging
activity on DPPH radical]
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Kamei
T, H Kumano, K Iwata, Y Nariai, T Matsumoto : The effect of a
traditional Chinese prescription for a case of lung carcinoma
JOURNAL OF ALTERNATIVE AND COMPLEMENTARY MEDICINE 6(6):557-559
2001 [Summary:To examine the effectiveness
of Ninjin Yoei To (NYT; Ren-Shen-Yang-Rong-Tang in Chinese
medicine; Kotaro Pharmaceutical Co., Ltd., Osaka, Japan), one of
the traditional herbal medicines, against lung carcinoma.
SETTING: The Nursing Center Himawari DESIGN, PATIENT, AND
PREPARATION: The regular dosage of NYT (15 g/d) was prescribed
for 7 weeks to one elderly patient with lung carcinoma. The daily
standard dose of NYT is prepared from dried extract obtained from
12 crude natural substances, ginseng, cinnamon bark, Japanese
angelica root, astragalus root, peony root, citrus unshiu peel,
rehmannia root, polygala root, atractylodes rhizome, schisanda
fruit, poria sclerotium, and glycyrrhiza. NYT is certified by the
Japanese Ministry of Health and Welfare. RESULTS: The tumor
marker levels (CEA and CA19-9) decreased and the scores of
yin-yang and xu-shi inverted from negative and positive during 7
weeks. The patient's cough disappeared and her appetite
recovered. CONCLUSION: NYT has a positive effect on life
expectancy for patients with malignancy. The diagnostic scoring
system in yin-yang and xu-shi and prescription of Chinese herb
may be available to gain control over a patient's health]
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Kobayashi
K, Y Saito, I Nakazawa, F Yoshizaki : Screening of crude
drugs for influence on amylase activity and postprandial blood
glucose in mouse plasma BIOLOGICAL & PHARMACEUTICAL
BULLETIN. 23(10):1250-1253 2001 [Summary: Screening of
crude drugs for inhibitory activity on alpha-amylase in mouse
plasma was performed. Hot water extracts and ethanolic extracts
of Arecae Semen, Ephedrae Herba, Malloti Cortex, Rhei Rhizoma and
ethanolic extract of Moutan Cortex inhibited enzyme activity in
isolated mouse plasma strongly and dose-dependently. However, the
effects of these 9 extracts were not observed in the plasma when
they were administered intraperitoneally or orally. Ethanolic
extract of Arecae Semen also showed a depressive effect on
elevation of postprandial blood glucose]
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Matsuda,H:
Regular Articles - Bioactive Constituents of Chinese Natural
Medicines. VI. Moutan Cortex. (2): Structures and Radical
Scavenging Effects of Suffruticosides A, B, C, D, and E and
Galloyl-oxypaeoniflorin CHEMICAL AND PHARMACEUTICAL BULLETIN
49(1):69-72 2001
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Matsumoto
K, Y Murakami, K Tabata, H Watanabe : Ameliorative effects of
paeoniflorin, a major constituent of peony root, on adenosine A1
receptor-mediated impairment of passive avoidance performance and
long-term potentiation in the hippocampus BIOLOGICAL &
PHARMACEUTICAL BULLETIN. 24(5):496-500 2001
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MillerMartini
D M , R Y Chan, N Y Ip, S J Sheu, Y H Wong : A reporter gene
assay for the detection of phytoestrogens in traditional Chinese
medicine PHYTOTHERAPY RESEARCH 15(6):487-492 2001 [Summary:
Bupleurum & Peony Formula (Jia Wei Xiao Yao San) is a herbal
formula which possesses a clinical history for the treatment of
menopausal syndrome and menstrual irregularity. The present
investigation reports the ability to monitor the formula's
phytoestrogen content that will allow for the implementation of a
standardization protocol that is based on a quantifiable
biological response. Utilizing an oestrogen-sensitive chimeric
receptor/reporter gene element which has been stably transfected
into HeLa cells, the botanical formula was shown to induce the
expression of the reporter gene, luciferase, in a dose dependent
manner. Pretreatment of the HeLa cells with the botanical formula
produced a 5-fold increase in bioluminescence compared with the
control. Additionally, our studies showed that the response of
the cells, when challenged by the botanical formula, was
oestrogen specific. Pretreatment of the cells with tamoxifen
effectively blocked the activation of the chimeric oestrogen
receptor by the botanical formula. The cell line provides a
sensitive assay that can easily detect the presence of
phytoestrogens in complex botanical formulas]
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Nawaz
H R A Malik, P M Khan, S Shujaat, A Rahman : A novel
beta-glucuronidase inhibiting triterpenoid from Paeonia emodi
..CHEMICAL AND PHARMACEUTICAL BULLETIN 48(11):1771-1773 2001
[Summary: A novel beta-glucuronidase inhibiting triterpene
(1) has been isolated from the chloroform fraction of Paeonia
emodi beta-glucuronidase inhibit established ase chloroform
fraction of Pa
11,beta,5alpha,23,24-pentahydroxy-30-norolean-12,20(29)-d
ien-28-oic acid on the basis of spectroscopic analysis, including
high resolution mass spectroscopy, one and two-dimensional NMR
techniques. Oleanolic acid, betulinic acid, ethyl gallate, methyl
grevillate and 1,5-dihydroxy-3-methylanthraquinone are also
reported for the first time from Paeonia emodi.]
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Oh
G S, H O Pae, H Oh, S G Hong, I K Kim, K Y Chai, Y G Yun, T O
Kwon, H T Chung : In vitro anti-proliferative effect of
1,2,3,4,6-penta-O-galloyl-beta-D-glucose on human hepatocellular
carcinoma cell line, SK-HEP-1 cells CANCER LETTERS
174(1):17-24 2001 [Summary: The root of Paeonia
suffruticosa ANDREWS is an important Chinese crude drug used in
many traditional prescriptions.
1,2,3,4,6-penta-O-galloyl-beta-D-glucose (PGG), a major component
of this crude drug, was found to exhibit in vitro
growth-inhibiting effect on human hepatocellular carcinoma cell
line, SK-HEP-1 cells. The growth-inhibitory effect was related to
the ability of PGG not only to cause a G(0)/G(1) phase arrest but
also to suppress the activation of nuclear factor-kappa B.
Neither apoptosis nor necrosis was observed in the cells treated
with PGG. These findings suggest that PGG could be a candidate
for developing a low-toxic anticancer agent.]
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Orlikowski,L.B;
Skrzypczak,Cz; Jaworska-Marosz,A. 2001. Influence
of grapefriut extract on the growth and development of Botrytis
spp. and gray mould development on lily and peony.
Bull.Pol.Acad.Biol. 49 (4). 375-379.
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Page,
Martin & Sinnott, Mike, 2001, P. japonica. Curtis's
Botanical Magazine. Vol. 18, 1, pp. 79-84.May 2001 [The
Japanese Paeonia japonica (Makino) Miyabe & Takeda
(Paeoniaceae) is illustrated. Its taxonomy, distribution, and
cultivation requirements are discussed and a full description of
the species is provided.]
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Rieck,
I, 2001, Strauchpäonien aus Heze, Gartenpraxis
7:16-21
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Sang,
T., Ferguson, D. :
Speciation
through homoploid hybridization between allotetraploids
in peonies (Paeonia) PNAS: PROCEEDINGS OF THE NATIONAL
ACADEMY OF SCIENCES
98(7):3915-3919 2001 [Summary:
Phylogenies of Adh1 and Adh2 genes suggest that a widespread
Mediterranean peony, Paeonia officinalis, is a homoploid hybrid
species between two allotetraploid species, Paeonia peregrina and
a member of the Paeonia arietina species group. Three
phylogenetically distinct types of Adh sequences have been
identified from both accessions of P. officinalis, of which two
types are most closely related to the two homoeologous Adh loci
of the P. arietina group and the remaining type came from one of
the two Adh homoeologs of P. peregrina. The other Adh homoeolog
of P. peregrina was apparently lost from the hybrid genome,
possibly through backcrossing with the P. arietina group. This is
a documentation of homoploid hybrid speciation between
allotetraploid species in nature. This study suggests that hybrid
speciation between allotetraploids can occur without an
intermediate stage of genome diploidization or a further doubling
of genome size]
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Shimizu,
K. , Sakata, Y., Shiraishi, A., Aoki, N., Wang, L.-S., Hashimoto,
F. : Analysis
of Petal Anthocyanins to Investigate Flower Coloration of
Zhongyuan (Chinese) and Daikon Island (Japanese) Tree Peony
Cultivars JOURNAL OF
PLANT RESEARCH 114(1113):33-44 2001 [Summary:A
comparative study was conducted on Zhongyuan (130, Chinese) and
Daikon Island (37, Japanese) tree peony cultivars to analyze
anthocyanin constitutions in the petals in relation to flower
colors. The distribution of flower hues displayed by loci of
colors on a CIELAB (international Commission on Illumination)
diagram was found to be similar between cultivars of the two
areas. However, the flower colors of a traditional classification
did not correspond with the CIELAB hues. An identification by
chemical structure of three anthocyanidins in the petals
(pelargonidin, Pg; cyanidin, Cy and peonidin, Pn) classified the
cultivars into four flower groups, i.e. Pn, Pg; Pn, Pg>Cy; Pn,
Cy and Pn, Cy>Pg groups. Each group consequently specified
significant features among CIELAB color notation and petal
pigmentation, being adequate to characterize tree peony flowers
as similar between Zhongyuan and Daikon Island cultivars, thus
the cultivars of the two areas are suggested to be related to one
another.]
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Wang,
H., van Staden, J. : Establishment of in vitro cultures of
tree peonies South African journal of animal science =
Suid-Afrikaanse tydskrif vir veekunde V67(2):358-361 2001
(direct
link to Infotrieve)
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Wang,
L.S., Hashimoto, F., Shiraishi, A., Aoki, N., Li, J.j., Shimizu,
K., Sakata, Y. : Phenetics in Tree Peony Species from China
by Flower Pigment Cluster Analysis JOURNAL OF PLANT RESEARCH
114(1115):213-222 2001 [Summary:Petal pigment
compositions were used as markers to study the phenetic
relationships among seven wild tree peony species of Paeonia
section Moutan DC. (fifteen accessions) from China. As the
pigment markers, five anthocyanins together with three flavone
a..]
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Wen
ZM, Xu LX. [Isolation and elucidation
of chemical constituents of shandanshaoyao decoction
(II)][Article in Chinese] Zhongguo Zhong Yao Za Zhi.
2001 Jul;26(7):474-7. [OBJECTIVE: To
study the chemical constituents of Shandanshaoyao Decoction.
METHOD: The sample was prepared by boiling water, then
precipitated by 75% of ethanol. The ethanol soluble fraction was
extracted by chloroform, ethyl acetate and n-butanol,
respectively. The extracts were isolated using macroreticular
resin, silica gel and polyamide column chromatography, and then
the chemical constituents were identified by chemical and
spectroscopic methods. RESULT: Nine compounds were isolated from
the n-butanol extract and water soluble fraction, and elucidated
as vitexin, quercetin, hyperoside, rutin, paeoniflorin,
protocatechaldehyde, (+)-catechin, danshensu and citric acid
respectively. CONCLUSION: The chemical constituents of
traditional Chinese medicinal preparations Shandanshaoyao
Decoction were reported for the first time.] Institute of
Materia Medica, Chinese Academy of Medical Sciences, Peking Union
Medical College, Beijing 100050, China.
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Wu,
S. H., Luo, X. D., Ma, Y. B., Hao, X. J., Wu, D. G: A
new 24, 30-dinortriterpenoid from Paeonia delavayi.
CHINESE CHEMICAL LETTERS 12(4):345-346
2001
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Xiangming,
C. , Guosheng, Z., Shengwang, Z. : RAPD
Analysis of Tree Peony Cultivars YUAN I HSUEH PAO
28(4):370-372 2001 [Summary:
Five paeonol glycosides, suffruticosides A, B, C, D, and E, and a
monoterpene glucoside, galloyl-oxypaeoniflorin, were isolated
from the glycosidic fraction of Chinese Moutan Cortex, the root
cortex of Paeonia suffruticosa Andrews, together with paeonolide,
apiopaeonoside, galloyl-paeoniflorin, oxypaeoniflorin, and
paeoniflorin. The structures of five suffruticosides and
galloyl-oxypaeoniflorin were elucidated on the basis of chemical
and physicochemical evidence. Suffruticosides A, B, C, and D,
galloyl-oxypaeoniflorin, and galloyl-paeoniflorin exhibited more
potent radical scavenging effects than alpha-tocopherol.]
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Yoshikawa,
Masayuki , Ohta, Toshio, Kawaguchi, Atsuhiro, Matsuda, Hisashi:
Bioactive constituents of Chinese natural
medicines. VI. Moutan Cortex. (2): Structures and radical
scavenging effects of suffruticosides A, B, C, D, and E and
galloyl-oxypaeoniflorin. CHEMICAL AND PHARMACEUTICAL
BULLETIN 49(1):69-72 2001 [Summary:
Five paeonol glycosides, suffruticosides A, B, C, D, and E, and a
monoterpene glucoside, galloyl-oxypaeoniflorin, were isolated
from the glycosidic fraction of Chinese Moutan Cortex, the root
cortex of Paeonia suffruticosa Andrews, together with paeonolide,
apiopaeonoside, galloyl-paeoniflorin, oxypaeoniflorin, and
paeoniflorin. The structures of five suffruticosides and
galloyl-oxypaeoniflorin were elucidated on the basis of chemical
and physicochemical evidence. Suffruticosides A, B, C, and D,
galloyl-oxypaeoniflorin, and galloyl-paeoniflorin exhibited more
potent radical scavenging effects than alpha-tocopherol.]
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Yoshikawa
M, T Ohta, A Kawaguchi, H Matsuda : Bioactive
constituents of Chinese natural medicines. V. Radical scavenging
effect of Moutan Cortex. (1): Absolute stereostructures of two
monoterpenes, paeonisuffrone and paeonisuffral CHEMICAL
AND PHARMACEUTICAL BULLETIN 48(9):1327-1331 2001 [Summary:
The methanolic extract and the ethyl acetate-soluble and
methanol-eluted fractions from Chinese Moutan Cortex, the roots
of Paeonia suffruticosa ANDREWS, were found to exhibit scavenging
effect on 1,1-diphenyl-2-picrylhydrazyl radical and superoxide
anion radical generated by the xanthine-xanthine oxidase system.
Two monoterpenes called paeonisuffrone and paeonisuffral were
isolated from the ethyl acetate-soluble fraction. Their absolute
stereostructures were elucidated on the basis of chemical and
physiochemical evidence, which included the application of a
modified Mosher's method and lipase catalyzed debenzoylation
reaction.]
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Yoshitomi
H, A Yagi, N Okamura, T Maki, H Miyauchi, M Shimoe, S Yokono :
Simultaneous determination of glycyrrhizin,
glycyrrhetic acid and glycyrrhetic acid mono-glucuronide in
Shakuyaku-kanzo-to incubated with rat feces by semi-micro
high-performance liquid chromatography BIOLOGICAL &
PHARMACEUTICAL BULLETIN. 24(10):1161-1164 2001 [Summary:
A method for semi-micro high-performance liquid chromatography
(HPLC) has been established for the simultaneous determination of
glycyrrhizin (GL), glycyrrhetic acid (GA) and glycyrrhetic acid
mono-glucuronide (GAMG) in incubation mixtures of rat feces with
Shakuyaku-kanzo-to decoction (combination of licorice root and
peony root). The analysis could be accomplished within 20 min
with a TSKgel ODS-80TsQA (150 x 2.0 mm i.d.) column by linear
gradient elution using a mobile phase containing aqueous
phosphoric acid and acetonitrile at a flow rate of 0.2 ml x
min(-1), a thermostatic oven at 25 degrees C, and detection at
254 nm. The detection limits of these compounds were 0.1-0.85
pmol per injection (5 microl). The concentrations of GL and its
metabolites in the incubation mixture after continuous
consumption of Shakuyaku-kanzo-to were significantly different
compared with those of untreated control. GL-hydrolysis of rat
feces was enhanced by pre-consumption of Shakuyaku-kanzo-to.]
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Zhang,
K., Fang, Y.-X., Huang, J.-M.: Extraction
of Paeonol from Cortex Moutan by Supercritical CO~2. FINE
CHEMICALS -DALIAN- 18(4):201-202 2001
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Zhimin,
G., Yan, W., Lianying, W. The recent development of research
on propagation and breeding of peony Pei-Ching Lin Yeh ta
Hsueh 23(4):75-79 2001
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Carsten
Burkhardt's Web
Project Paeonia
- The
Peony Library
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Paeonia-Literatur
2001
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